Pro-xylane, scientifically termed as Hydroxypropyl Tetrahydropyranthriol, is derived from xylose, a sugar abundant in oak trees. In this blog post, SACH BIOTECH will share with you the multiple benefits of CAS No.868156-46-1 Pro-xylane powder for skin health and anti-aging.
Structural Significance and Bioactivity
The molecular architecture of Pro-xylane is carefully designed, with β-glycosidic bonds being crucial for its bioactivity. The compound's chiral carbon at the 7th position presents different hydroxyl stereoconfigurations, leading to varying proportions of diastereomers. Studies suggest that a 70/30 diastereomer ratio (β, S) confers superior biological activity, making Pro-xylane a potent candidate for skin health applications.
Enhancing Dermal Matrix Structure
Polysaccharides are vital for maintaining the structural integrity of the dermal matrix, particularly the collagen fiber networks. With aging, a decrease in GAGs is observed, affecting skin's mechanical properties. Pro-xylane addresses this by stimulating the synthesis of GAGs and proteoglycans (PGs), thereby preserving the matrix structure and enhancing skin's mechanical resilience.
Promoting Collagen Synthesis and Elasticity
As a xylose derivative, Pro-xylane exhibits anti-aging activity by promoting collagen synthesis, which strengthens and elasticizes the skin, ameliorating fine lines, and delaying the aging process. Its ability to increase collagen production in the dermis indirectly through GAG synthesis contributes to dermal repair, skin elasticity, and firmness.
Dermal-Epidermal Junction (DEJ) Activation
Pro-xylane also acts at the DEJ, fostering the synthesis of collagen VII and IV, which tightens the connection between the epidermis and dermis. This results in a fuller, firmer, and more elastic appearance of the skin, addressing the visible signs of aging.
Clinical Evidence and Wound Healing
Clinical studies provide compelling evidence of Pro-xylane's efficacy. In a wound healing study, Pro-xylane demonstrated the ability to promote keratinocyte migration and proliferation, accelerating wound closure. A randomized, placebo-controlled trial involving 41 female volunteers showed significant improvements in skin wrinkles, elasticity, and radiance after six months of using a Pro-xylane-containing cream.
Anti-Aging and Dynamic Pattern Research
Further research has shown that Pro-xylane reduces dynamic wrinkles and improves traditional skin aging indicators. A high-speed imaging system captured the skin's response to dynamic facial expressions, revealing that Pro-xylane significantly mitigated the appearance of both dynamic and static wrinkles over a four-week period.
Application in Skincare Formulations
Pro-xylane's role as a non-ionic surfactant with dispersing and emulsifying properties makes it an ideal ingredient for skincare formulations. It aids in the absorption of other active ingredients, enhancing their penetration and overall effectiveness.
Conclusion
Pro-xylane's multifaceted benefits for skin health are undeniable. From its structural significance to its clinical validation, this C-glycoside stands as a beacon of innovation in the skincare industry. As we continue to explore sustainable and effective solutions for skin aging, Pro-xylane's role in enhancing skin elasticity, reducing wrinkles, and promoting overall skin health is set to shape the future of cosmeceuticals.
CAS No.868156-46-1 Pro-xylane Powder Supplier - SACH BIOTECH
After 15 years of development, SACH BIOTECH has established a strong R&D team and its own production base, which can adjust in time according to market demand to meet the special requirements of different customers for products. If you need various cosmetic raw materials, please contact us!
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